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Publications

  1. Williams, R., Martin, S., Lawrence, j., Norman, V., O'Neil-Johnson, M., Eldridge, G., Starks, C., "Isolation and Identification of the Novel Tubulin Polymerization Inhibitor Bifidenone," J. Nat. Prod., 2016, Accepted, Special Issue in Honor of Professor Phil Crews
  2. Biggs, B., Rouck, J., Kambalyal, A., Arnold, W., Lim, C., De Mey, M., O'Neil-Johnson, M., Starks, C., Das, A., Ajikumar, P., "Orthogonal Assays Clarify the Oxicative Biochemistry of Taxol P450 CYP725A4," ACS Chem. Biol., 2016, 11, 1445-1451
  3. Zerbe P., Rodriguez S., Mafu S., Chiang A., Sandhu H., O’Neil-Johnson M., Starks C., Bohlmann J., "Exploring Diterpene Metabolism in Non-model Sspecies: Transcriptome-enabled Discovery and Functional Characterization of Labda-7, 13E-Dienyl Diphosphate Synthase from Grindelia robusta," The Plant Journal, 2015, 83, 783-793
  4. Augustin, M., Ruzicka, D., Shukla, A., Augustin, J., Starks, C., O'Neil-Johnson, M., McKain, M., Evans, B., Barrett, M., Smithson, A., Wong, G., Deyholos, M., Edger, P., Pires, J., Leebens-Mack, J., Mann, D., Kutchan, T., "Elucidating Steroid Alkaloid Biosynthesis in Veratrum californicum: Production of Verazine in Sf9 Cells," The Plant Journal, 2015, 82, 991-1003
  5. Zerbe, P., Chiang, A., Dullat, H., O'Neil-Johnson, M., Starks, C., Hamberger, B., Bohlmann, J., "Diterpene Synthases of the Biosynthetic System of Medicinally Active Diterpenoids in Marrubium vulgare," The Plant Journal, 2014, 79, 914-927 Identifying Biosynthetic Intermediates at the Microgram Scale
  6. Kilgore, M., Rolf, M., Starks, C.M., O'Neil-Johnson, M., Kutchan, T.M., "Cloning and Characterization of a Norbelladine 4'-O-Methyltransferase Involved in the Biosynthesis of the Alzheimer's Drug Galanthamine in Narcissus spp." PLOS One, 2014, DOI: 10.1371/journal.pone.0103223 - Identifying Biosynthetic Intermediates at the Microgram Scale
  7. Starks, C.M.; Norman, V.L.; Williams, R.B.; Goering, M.G.; Rice, S.M.; O'Neil-Johnson, M.A.; Eldridge, G.R. "Antibacterial Activity of Taxodium ascendens Diterpenes Against Methicillin-resistant Staphylococcus aureus." Natural Product Communications, 2014, 9 (8), 1129-1130
  8. La Clair, J., Loveridge, S., Tenney, K., O'Neil-Johnson, M., Chapman, E., Crews, P., "In Situ Natural Product Discovery via an Artificial Marine Sponge." PLOS One, 2014, 9 (7), DOI: 10.1371/journal.pone.0100474
  9. Williams, Russell; Du, Lin; Norman, Vanessa; Goering, Matt; O'Neil-Johnson, Mark; Woodbury, Scott; Albrecht, Matthew; Powell, Douglas; Cichewicz, Robert; Eldridge, Gary; Starks, Courtney "Diterpenes from the Endangered Goldenrod Solidago shortii." Journal of Natural Products, 2014, 77 (6), 1438-1444
  10. Starks, C.M.; Williams, R.B.; Norman, V.L.; Rice, S.M.; O'Neil-Johnson, M.A.; Lawrence, J.A.; Eldridge, G.R. "Antibacterial Chromene and Chromane Stilbenoids from Hymenocardia acida." Phytochemistry, 2014, 98,216-222
  11. Williams, Russell; Norman, Vanessa; Goering, Matt; O'Neil-Johnson, Mark; Eldridge, Gary; Starks, Courtney "Acetylated Dammarane-type Bisdesmosides from Combretum inflatum." Journal of Natural Products, 2013, 76, 1592-1597
  12. Williams, R.B.; Martin, S.M.; Hu, J.F.; Norman, V.L.; Goering, M.G.; Loss, S.; O'Neil-Johnson, M.A.; Eldridge, G.R.; Starks, C.M. "Cytotoxic and Antibacterial Beilschmiedic Acids from a Gabonese Species of Beilschmiedia." Journal of Natural Products, 2012, 75, 1319-1325.
  13. Starks, C.M.; Williams, R.B.; Norman, V.L.; Lawrence, J.A.; O'Neil-Johnson, M.A.; Eldridge, G.R. "Phenylpropanoids from Phragmipedium calurum and their Antiproliferative Acitivity." Phytochemistry, 2012, 82, 172-175
  14. Starks, C.M.; Williams, R.B.; Rice, S.M.; Norman, V.L.; Lawrence, J.A.; Goering, M.G.; O'Neil-Johnson, M.; Hu, JF; Eldridge, G.R. "Cytotoxic Cyclohexene Derivatives from Monanthotaxis congoensis." Phytochemistry, 2012, 74, 185-189
  15. Williams, R.B.; Martin, S.M.; Hu, J.F.; Garo, E.; Rice, S.M.; Norman, V.L.; Lawrence, J.A.; Hough, G.W.; Goering, M.G.; O'Neil-Johnson, M.A.; Eldridge, G.R.; Starks, C.M. "Isolation of Apoptosis-Inducing Stilbenoids from Four Members of the Orchidaceae Family." Planta Medica, 2012, 78(2), 160-165.
  16. Olson, K.M.; Starks, C.M.; Williams, R.B.; O'Neil-Johnson, M.; Huang, Z.; Ellis, M.; Reilly, J.; Eldridge, G.R. "Novel Pentadecenyl Tetrazole Enhances Susceptibility of MRSA Biofilms to Gentamicin", Antimicrobial Agents and Chemotherapy, 2011, 55(8) 3691-3695
  17. Starks, C.M; Williams, R.B.; Norman, V.L.; Lawrence, J.; Goering, M.G.; O'Neil-Johnson, M.; Hu, J.F.; Rice, S.M.; Eldridge, G.R. Abronione, a rotenoid from the desert annual Abronia villosa. Phytochemistry Letters, 2011, 4, 72-74
  18. Williams, R.B.; Hu, J.F.; Olson, K.M.; Norman, V.L.; Goering, M.G.; O'Neil-Johnson, M.; Eldridge, G.R.; Starks, C.M. Antibiotic Indole Sesquiterpene Alkaloid from Greenwayodendron suaveolens with a New Natural Product Framework. Journal of Natural Products, 2010, 73, 1008-1011
  19. Ye, M.; Zhao, Y.; Norman, V.L.; Starks, C.M.; Rice, S.M.; Goering, M.G.; O'Neil-Johnson, M.; Eldridge, G.R.; Hu, JF. Antibiofilm phenylethanoid glycosides from Penstemon centranthifolius. Phytother Res. 2010, 24(5), 778-81
  20. Starks, C.; Williams, R.B.; Goering, M.G.; O'Neil-Johnson, M.; Norman, V.L.; Hu, J.F.; Garo, E.; Hough, B.; Rice, S.M.; Eldridge, G.R. Antibacterial Clerodane Diterpenes from Solidago vigaurea. Phytochemistry, 2010, 71, 104-109
  21. Fan, H., Starks, C.M., Hughey, H., Eldridge, G.R., Hu, J.F. Natural anti-HCV Agents, Drugs of the Future, 2009, 34(3), 223-236
  22. Garo, E.; Huang, C.S.; Williams, R.B.; Olson, K.M.; Hu, J.F.; Rice, S.M.; Hough, B.; Goering, M.G.; O'Neil-Johnson, M.; Eldridge, G.R. Dammarane-Type Triterpene Glycosides from Oncoba manii Active against Methicillin-Resistant Staphylococcus aureus. Planta Medica, 2009, 75, 541-543
  23. Hu, J.F.; Starks, C.; Williams, R.B.; Rice, S.M.; Norman, V.L.; Olson, K.M.; Hough, B.; Goering, M.G.; O'Neil-Johnson, M.; Eldridge, G.R. Secoiridoid Glycosides from the Pitcher Plant Sarracenia alata. Helvetica Chimica Acta, 2009, 92, 273-28
  24. Hu, J.F.; Eldridge, G.R.; Yu, Y.H.; O'Neil-Johnson, M. High-throughput Natural Product Chemistry Methods and the Application of the Capillary NMR Probe, Prog. Chem., 2008, 20 (4), 429-440
  25. Hu, J.F.; Starks, C.; Garo, E.; Hough, G.; Rice, S.; Goering, M.G.; O'Neil-Johnson, M.; Eldridge, G.R. Laxanol, a new 2,5-diaryl-3,4-dihydroxymethyltetrahydrofuran type lignan from Justicia laxa. Journal of Chemical Research, 2008, 1, 20-21
  26. Cegelski, L.; Marshall, G.R.; Eldridge, G.R.; Hultgren, S.J. The Biology and Future Prospects of Antivirulence Therapies, Nature Rev. Microbiol. 2008, 6, 17-27
  27. Garo, E.; Eldridge, G.R.; Goering, M.; DeLancey Pulcini, E.; Hamilton, M.; Costerton, J.; James, G. Asiatic Acid and Corosolic Acid Enhance the Susceptibility of Pseudomonas aeruginosa Biofilms to Tobramycin. Antimicrob. Agents Chemother., 2007, 51, 1813-1817
  28. Hu, J.F.; Garo, E.; Hough, G.; Goering, M.; O’Neil-Johnson, M.; Eldridge, G.R.
    Acuminatanol, the first 2',2'''-bis-dihydrobiflavonol from the Aqueous Extract of Trichoscypha acuminata; Tetrahedron Letters, 2007, 48, 5747-5749
  29. Hu, J.F.; Garo, E.; Hough, G.; Goering, M.; Yoo, H.D; O’Neil-Johnson, M.; Eldridge, G.R.
    Isoflavones from Psorothamnus arborescens via High-throughput Natural Product Chemistry Methods; Journal of Chemical Research, 2007, 5, 296-297
  30. Garo, E.; Hu, J.F.; Hough, G.; Goering, M.; O’Neil-Johnson, M.; Eldridge, G.R. Stilbenes from the Orchid Phragmipedium sp. Journal of Natural Products, 2007, 70, 968-973
  31. Hu, J.F.; Patel, R.; Li, B.; Garo, E.; Hough, G.; Goering, M.; Yoo, H.D.; O’Neil-Johnson, M.; Eldridge, G.R. Anti-HCV Bioactivity of Pseudoguaianolides from Parthenium hispitum. Journal of Natural Products, 2007, 70, 604-607
  32. Hu, J.F.; Garo, E.; Hough, G.W.; Goering, M.G.; O’Neil-Johnson, M.; Eldridge, G.R. Antibacterial, Partially Acetylated Oligorhamnosides from Cleistopholis patens. J.Nat. Prod. 2006, 69, 585-590
  33. Hu, J.F.; Garo, E.; Goering, M.G.; Pasmore, M.; Yoo, H.D.; Esser, T.; Sestrich, J.; Cremin, P.C.; Hough, G.W.; Perrone, P.; Lee, Y.; Le, N.; O’Neil-Johnson, M.; Costerton, J.W.; Eldridge, G.R. Bacterial Biofilm Inhibitors from Diospyros dendo. J. Nat. Prod. 2006, 69, 118-120
  34. Hu, J.F.; Garo, E.; Yoo, H.D.; Cremin, P.A.; Goering, M.G.; O’Neil-Johnson, M.; Eldridge, G.R. Cyclolignans from Scyphocephalium ochocoa via high-throughput natural product chemistry methods. Phytochemistry, 2005, 66, 1077-1082
  35. Peti, W.; Page, R.; Moy, K.; O’Neil-Johnson, M.; Wilson, I.A.; Stevens, R.C.; and Wüthrich, K. Towards Miniaturization of a Structural Genomics Pipeline Using Micro-expression and Microil NMR. J.Struct.Funct.Genomics, 2005, 6, 259-267
  36. Ren, D.; Zuo, R.; Gonzalez, A.F.; Bedzyk, L.A.; Eldridge, G.R.; Pasmore, M.E.; Wood, T.K. Differential Gene Expression for Investigation of Escherichia coli Biofilm Inhibition by Plant Extract Ursolic Acid. Appl. Environ. Microbiol. 2005, 71, 4022-4034
  37. Hu, J.F.; Garo, E.; Yoo, H.D.; Cremin, P.A.; Zeng, L.; Goering, M.G.; O’Neil-Johnson, M.; Eldridge, G.R. Application of capillary-scale NMR for the structure determination of phytochemicals. Phytochem. Anal. 2005, 16, 127-133
  38. Yoo, H.D.; Cremin, P.A.; Zeng, L.; Garo, E.; Williams, C.T.; Lee, C.M.; Goering, M.G.; O'Neil-Johnson, M.; Eldridge, G.R.; Hu, J.F. Suaveolindole, a New Mass-Limited Antibacterial Indolosesquiterpene from Greenwayodendron suaveolens Obtained via High-Throughput Natural Products Chemistry Methods. J.Nat.Prod. 2005, 68, 122-124
  39. Hu, J.F.; Yoo, H.D.; Williams, C.T.; Garo, E.; Cremin, P.A.; Zeng, L.; Vervoort, H.C.; Lee, C.M.; Hart, S.M.;Goering, M.G.; O’Neil-Johnson, M.; Eldridge, G.R. Miniaturization of the Structure Elucidation of Novel Natural Products – Two Trace Antibacterial Acylated Caprylic Alcohol Glycosides from Arctostaphylos pumila. Planta Med. 2005, 71, 176-180
  40. Olson, D.L.; Norcross, J.A.; O'Neil-Johnson, M.; Molitor, P.F.; Detlefsen, D.J.; Wilson, A.G.; and Peck, T.L. Microflow NMR: Concepts and Capabilities. Anal. Chem. 2004, 76, 2966-2974
  41. Peti, W.; Norcross, J.; Eldridge, G.R.; O’Neil-Johnson, M. Biomolecular NMR Using a Microcoil NMR Probe – New Technique for the Chemical Shift Assignment of Aromatic Side Chains in Proteins. J. Am. Chem. Soc. 2004, 126, 5873-5878
  42. Cremin, P.A.; Zeng, L. High-Throughput Analysis of Natural Product Compound Libraries by Parallel LC-MS Evaporative Light Scattering Detection. Anal. Chem. 2002, 74, 5492-5500
  43. Eldridge, G.R.; Vervoort, H.C.; Lee, C.M.; Cremin, P.A.; Williams, C.T.; Hart, S.M.; Goering, M.G.;O’Neil-Johnson, M.; Zeng, L. High-Throughput Method for the Production and Analysis of Large Natural Product Libraries for Drug Discovery. Anal. Chem. 2002, 74, 3963-3971